The Benefits of Resistance and Weight-Bearing Exercise for Men on Androgen Deprivation Therapy (ADT)

Androgen Deprivation Therapy (ADT) is a cornerstone of treatment for many men navigating prostate cancer. While highly effective at managing the disease, the reduction in testosterone can lead to significant physical side effects, including decreased muscle mass, increased body fat, and a reduction in bone mineral density. At Duke Men’s Health, we advocate for a proactive approach: using resistance and weight-bearing exercise to counteract these changes and protect your long-term vitality.

Why Exercise is Essential During ADT

Low testosterone levels from ADT can shift your body’s composition and bone health. Without intervention, many men experience “sarcopenia” (muscle wasting) and an increased risk of osteoporosis. However, clinical research consistently shows that targeted exercise is the most effective way to manage these metabolic shifts.

• Bone Health: Weight-bearing exercises stimulate bone-forming cells, helping to maintain bone density and reduce fracture risk.
• Metabolic Support: Resistance training helps regulate blood sugar levels and combat the weight gain often associated with hormonal therapy.
• Physical Function: Maintaining muscle strength ensures you can continue your daily activities, hobbies, and sports with confidence.
• Mental Well-being: Regular physical activity is proven to reduce the fatigue and emotional stress that often accompany cancer treatment.

Our Recommended Exercise Pillars

A balanced program for men on ADT focuses on two primary types of movement to ensure comprehensive protection for the musculoskeletal system.

1. Progressive Resistance Training

Using weights, resistance bands, or bodyweight exercises (like squats and push-ups) forces your muscles to work against a load. This is the primary driver for maintaining muscle mass and strength during treatment.

2. Impact & Weight-Bearing Activities

Activities such as brisk walking, jogging, or low-impact aerobics provide the “mechanical loading” necessary to keep your bones strong. Even standing exercises that challenge your balance play a role in preventing falls and fractures.

The Specialist Physiotherapy Advantage

Starting an exercise program during cancer treatment can feel daunting. At Duke Men’s Health, our physiotherapists provide the expert supervision needed to ensure your program is safe, effective, and tailored to your current energy levels.

We monitor your progress, adjust intensities based on your treatment cycle, and ensure your technique protects your joints while maximizing your strength gains. Whether you are a regular at the gym or starting from scratch, we help you move with purpose and safety.